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3-Dose Malaria Vaccine Shows Promise in African Trial
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3-Dose Malaria Vaccine Shows Promise in African Trial

By Cara Murez HealthDay Reporter(HealthDay)FRIDAY, Jan. 6, 2023 (HealthDay News) – New research has confirmed that a three-dose malaria vaccine is both safe and effective in West African adults, including those previously exposed to malaria.Researchers at the University of Maryland Center for Vaccine Development and Global Health (CVD) led work on the Plasmodium falciparum sporozoite (PfSPZ) vaccine.The clinical trial, which included 80 participants, compared three doses of the PfSPZ vaccine against a placebo. Vaccine efficacy — a measure of how many vaccinated people got malaria — was 48% after six months and 46% at an 18-month follow-up.“Our study shows that the vaccine can be given to malaria-experienced adults in a highly endemic area and still provide protection, which is difficult...