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76ers vs. Knicks prediction, odds, spread, line: 2022 NBA picks, Nov. 4 best bets from proven model

Wells Fargo Center showcases an Eastern Conference matchup between division rivals on Friday. The Philadelphia 76ers host the New York Knicks for the first of four regular season meetings. Philadelphia is 4-5 overall but 3-1 in the last four games. New York is 3-4 overall but 0-3 on the road and on a three-game losing streak. Joel Embiid (illness) and Matisse Thybulle (ankle) are listed as questionable for the 76ers, with James Harden (foot) ruled out.

Caesars Sportsbook lists Philadelphia as a 3.5-point home favorite, and tip-off is scheduled for 7 p.m. ET. The total number of points Vegas thinks will be scored, or the over/under, is 220 in the latest Knicks vs. 76ers odds. Before you make any NBA predictions with the 76ers vs. Knicks match-up, you need to see the NBA predictions and betting advice from SportsLine’s advanced computer simulation model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past four seasons. The model enters Week 3 of the 2022-23 NBA season on a stunning 97-65 roll on all top-rated NBA picks that dates back to last season, returning more than $2,400. Anyone following it has seen huge returns.

Now, the model has set its sights on Sixers vs. Knicks and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model’s picks. Now, here are several NBA odds, betting lines, and trends for Knicks vs. 76ers:

  • Knicks vs. 76ers spread: 76ers -3.5
  • Knicks vs. 76ers over/under: 220 points
  • Knicks vs. 76ers money line: 76ers -160, Knicks +135
  • NYK: The Knicks are 3-4 against the spread this season
  • PHI The 76ers are 4-5 against the spread this season
  • Knicks vs. 76ers picks: See picks at SportsLine

Featured Game | Philadelphia 76ers vs. New York Knicks

Why the Knicks can cover

New York has a few clear edges in the metrics as this matchup arrives. The Knicks are above-average in overall defensive rating, yielding 1.11 points per possession, and New York is in the top three of the NBA in field goal percentage allowed (42.6%) and 2-point percentage allowed (48.9%). The Knicks are also in the top 10 in 3-point percentage allowed (33.5%) and blocked shots (5.9 per game). New York should be strong on the defensive glass against a Philadelphia team that is dead-last in offensive rebound rate (20.2%), and the 76ers are in the bottom five of the league in free throw creation, generating only 21.6 attempts per game.

On offense, New York’s projection is strong in the turnover margin. The Knicks are in the top 10 of the NBA in ball security, giving the ball away on only 13.5% of possessions, and the 76ers are in the bottom 10 in creating turnovers on defense. New York is also very good on the offensive glass, securing 32% of missed shots, and Philadelphia is allowing opponents to shoot 47.6% from the field.

Why the 76ers can cover

Philadelphia’s offense is off to a tremendous start. The Sixers are scoring 115.6 points per 100 possessions, ranking in the top five of the NBA in efficiency. Philadelphia is also in the top three of the league in field goal percentage (48.8%) and 3-point percentage (41.2%), with a top-five mark in turnovers (12.4 per game). The 76ers have multiple players averaging at least 22 points per game, and New York is in the bottom five of the NBA in defensive rebound rate (66.5%), turnover creation (12.4 per game), and steals (5.9 per game). 

On the defensive side, Philadelphia also has a few edges, including at the 3-point line. The 76ers are holding opponents to 33.3% shooting from beyond the arc, with New York shooting only 32.9% from 3-point range. Philadelphia is also strong at free throw prevention, yielding only 22.8 attempts per game, and New York is in the bottom half of the league in free throw creation and free throw accuracy on offense this season.

How to make 76ers vs. Knicks picks

SportsLine’s model is leaning Over on the point total, projecting the teams to combine for 226 points. The model also says one side of the spread hits in well over 50% of simulations. You can only see the model’s pick at SportsLine.

So who wins Knicks vs. Sixers? And which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its NBA picks, and find out. 

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